Hematocrit Evaluation for Identifying Risk of Cyanotic Nephropathy in Patients with Congenital Cyanotic Heart Disease Abstract Background: With modern advances in cardiac care, patients with congenital cyanotic heart disease (CCHD) are living longer. As a result of this, the medical community is recognizing an increasing prevalence of non-cardiac complications in these patients. One of the […]
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Category: Graduate Project
Stacy E. Legg: Oral Nicotinamide Reduces...
Oral Nicotinamide Reduces Actinic Keratoses in Adults with Sun-Damaged Skin ABSTRACT Background: Actinic keratoses (AKs) are skin lesions primarily caused by ultraviolet (UV) exposure. They are precancerous lesions and can develop into non-melanoma skin cancer. Exposure to UV radiation leads to the development of AKs by several mechanisms. UV radiation damages cellular DNA, depletes cellular […]
Alexander R. Christy: Extracorporeal Mem...
Extracorporeal Membrane Oxygenation for Near-Drowning Victims ABSTRACT Background: Drowning is the leading cause of death in children worldwide. Likewise, the survival rate of adults found in cardiac arrest by emergency medical personnel after a drowning event is 1.7%. Sequelae attached to near-drowning events are highly varied in type and severity and are often proportional to […]
Aaron Inouye: The Safety of TMP-SMX Use ...
The Safety of TMP-SMX Use in Patients Taking an ACE-I or ARB ABSTRACT Background: Angiotensin converting enzyme inhibitors (ACE-I) and angiotensin receptor blockers (ARB) are commonly used medications for hypertension, heart failure, and diabetes. Trimethoprim-sulfamethoxazole (TMP-SMX) is a commonly used antibiotic for many bacterial infections. While hyperkalemia is a known risk of each drug, little has […]
Gabrielle L. Engelhard: Dynamic MRI to D...
Dynamic MRI to Diagnose Spinal Canal Stenosis not Visualized on Standard Static MRI in patients With Cervical Spondylotic Myelopathy ABSTRACT Background: Cervical Spondylotic Myelopathy (CSM) is a common disease of the cervical spine that affects people during and after middle age. To date, imaging preformed preoperatively consists of MRI of the cervical spine in neutral position. […]
Matthew Biasca: Collagenase Clostridium ...
Collagenase Clostridium histolyticum Injections Can Be an Effective Alternative to Surgical Intervention in Moderate to Severe Dupuytren’s Contracture ABSTRACT Background:Dupuytren’s contracture is a common debilitating fibroproliferative disease of the hand. The current standard of care for moderate or severe Dupuytren’s is surgical fasciectomy. However, while surgery yields a significant initial correction of the contracture, the […]
Richard Nile: Nonfasting LDL-C as a Pred...
Nonfasting LDL-C as a Predictor of Cardiovascular Event Risk ABSTRACT Background: Cardiovascular health is often assessed through predictive tools that rely upon measured lipid values. It has long been held that lipids were most accurately measured with the patient in the fasting state; however, mounting evidence has suggested that nonfasting lipid measurements are not significantly […]
Stacy R. Joyce: Morphine in Myocardial I...
Morphine in Myocardial Infarction: Delay in Platelet Inhibition due to Morphine Administered to Patients Presenting with Acute Coronary Syndrome ABSTRACT Background:The American College of Cardiology Foundation/American Heart Association Task Force recommends morphine for patients with ST-elevation myocardial infarction and for patients undergoing primary percutaneous coronary intervention (PPCI). A drug-to-drug interaction between morphine and the preferred […]
Lauren Ljunghag: Subcutaneous Insulin in...
Subcutaneous Insulin in the Treatment of Diabetic Ketoacidosis in the Pediatric Population ABSTRACT Background: Diabetic ketoacidosis or DKA is an acute and fatal disease that is highly prevalent in the pediatric population. The current gold standard of treatment is continuous intravenous regular insulin (CIRI), which requires admission to the intensive care unit (ICU) and is […]
Michael Smith: Hop Extract, a Bittering ...
Hop Extract, a Bittering Component Used in Beer, Helps Reduce Visceral Obesity in Healthy Overweight Adults ABSTRACT Background: Humulus lupulus (hops) have long been used in beer brewing for their antimicrobial and bittering properties. Hops contain alpha acids, which during the boiling process of beer, get isomerized into iso-alpha-acids also called isohumulones. Research has postulated […]